In a terminal, enter the following: defaults write com.microsoft.Powerpoint NSQuitAlwaysKeepsWindows -bool false defaults write com.microsoft.Word NSQuitAlwaysKeepsWindows -bool false defaults write com.microsoft.Excel NSQuitAlwaysKeepsWindows -bool false The same thing can be done for any application in Lion. In order to find the application preference name, look at the files names found here (minus .savedState): ~/Library/Saved Application State…. Read more »